It is purely herbal and Ayurvedic formulation. These tablets have ingredients like kalimirch, giloy satva, shudha shilajeet, shudha kuchala, shudha vatsnabh etc. These ingredients have anti-inflammatory, analgesic, aphrodisiac, nerve stimulating properties thus helps to relieve symptoms like pain, stiffness associated with rheumatism along with improving overall wellness of central nervous system. These tablets are also beneficial in appetite by improving intestinal mobility as well as gastro-intestinal functions. These tablets have calming and soothing affect on the nerves thus improving the sleep quality and managing insomnia.

INGREDIENTS OF CAC NERVE PLUS TABLET:

• GHRITKUMARI( Aloe barbadensis) : It has anti-oxidant and anti-inflammatory properties thus helps to improve learning and memory. It also helps to improve the inflammation in the body . It also decrease the damage caused by free radicals in the body.
• KALIMIRCH (Piper nigrum) : It has anti-inflammatory and antioxidant properties thus helps to improve the nerve pain. It also protect the nerve cells and prevent early death of the cells. It also regulates the serotonin and melatonin functioning thus provide relief from stress, anxiety and fatigue.
• GILOY SATAV (Tinospora cordifolia) : It contain anti-inflammatory properties that helps to relieve the symptoms of arthritis. It also have analgesic properties that are beneficial in reducing joint and muscle pain.
• SHUDHA SHILAJEET( Asphaltum) : It has bioactive compound called fulvic acid which contributes to cognitive health by prevention of accumulation of Tau protein which is useful for nervous system but excessive accumulation can cause damage to brain cell.
• VISHMUSTYADI VATI : It contain ingredients like shudh kuchla, jaipala , lauh bhasm etc that helps to relieve symptoms nervous system disorders ,, abdominal pain, sciatica, rheumatic pain etc.
• HINGULESHWAR RASA : It has excellent result in management of Vata disorders. It provide relief from symptoms like pain, inflammation, stiffness and also remove toxic materials from the body.

USES OF CAC NERVE PLUS TABLET :

• Stimulate the nervous system.
• In insomnia
• In rheumatism
• Acts as aphrodisiac
• In Inflammation
• Improve appetite

COMPARED TO CAC NERVE PLUS TABLETS ITS ALLOPATHIC COUNTERPART IS PREGABALIN

Pregabalin comes under the class of drugs called Anti-convulsants.  It has anxiolytic, analgesic, anti-allodynic and anti-convulsant properties. When taken orally it reach peak plasma concentration within 1.5 hours.

MECHANISM OF ACTION :

It inhibits certain calcium channels in central nervous system and modulates the release of several neurotransmitters which send pain signal across nervous system.

It is available in market under brand name :

• Maxgalin
• Pregaba
• Pbren
• Peg
• Lyrica
• Pregalin
• Gabawin
• Neugaba
• Pregabid
• Pregeb

SIDE-EFFECT :

• Dizziness
• Vertigo
• Tremor
• Chest pain
• Hypotension
• Peripheral edema
• Confusion
• Nervousness
• Amnesia
• Pruritius
• Dry skin
• Urticaria
• Nausea
• Dry mouth
• Gastritis
• Back pain
• Leg cramps

WITHDRAWAL SYMPTOMS :

• Anxiety
• Nervousness
• Pain
• Insomnia
• Diarrhea
• Flu like symptoms
• Convulsions
• Hyper-hidrosis

Kutaj ghanvati is a classical Ayurvedic formulation which is pure herbal consists of stem bark of Kutaja as the main ingredient. The meaning of Ghan is dried powder or liquid or decoction and Vati is termed pills or tablets. The dried decoction of Kutaj in tablet form is kutaj ghan vati. Kutaj is an herb that is especially useful in loose motions, dysentery, and other digestive diseases. The botanical name of Kutaj is Holarrhena antidysenterica (Family: Apocynaceae).

INGREDIENTS:

1. Kutaja ( Holarrhena antidysenterica):

It is also known as Kurchi. It is a small deciduous tree with rough brown bark .It helps in removing the excess fire energy. It has tikta and kashaya rasa shows laghu or ruksha properties. It also shows cold potency which helps to pacify vata and pitta dosha. It is useful in treating diarrhea and dysentery, promotes digestion,

2. Ativisha (Aconitum heterophyllum):

This plant contains aconitic acid, tannic acid, starch, oleic acid,stearicglycerides .It helps in digestion of indigested food or increase secreation of digestive juices , removes warm infestation, purifies blood .It has tikta or katu rasa, laghu or ruksha guna and it also shows cold potency . It has beem purified by swedana process than it is consumed by human beings.

MEDICINAL PROPERTIES:

• Antimicrobial
• Antidiarrheal
• Anti -dysenteric
• Astringent
• Anthelmintic
• Detoxifier
• Hemostatic
• Anti-amoebic

 THERAPEUTIC INDICATION:

• Diarrhea
• Dysentery
• Amoebiasis
• Irritable Bowel Syndrome (IBS)
• Abdominal Pain/cramps due to Diarrhea

ALLOPATHIC COUNTERPART OF KUTAJ GHAN VATI ALONG WITH ITS SIDE EFFECTS:

LOPERAMIDE

BRAND NAME: IMODIUM

This medication is used to treat sudden diarrhea. It works by slowing down the movement of gut. This allows more time for reabsorption of fluids and nutrients make the stool more solid and less frequent. It belongs to the class of drugs called anti-diarrheal. The chemical formula of loperamide is C₂₉H₃₃ClN₂O_2.

SIDE EFFECTS:

1. Dizziness
2. Drowsiness
3. Dry mouth
4. Gas
5. Headache
6. Nausea
7. Vomiting
8. Tiredness

INTERACTION WITH OTHER MEDICATION:

• Alcohol
• Antifungal such as fluconazole
• Barbiturates such as Phenobarbital
• Carbamazepine
• Domperidone
• Mifepristone
• Tetrabenazine
• Nortriptyline
• _Ondasetron

CONTRAINDICATION:

• _{Age less than 10 years.}
• _{Liver problems}
• _{Bloody diarrhoea}
• _{Paralysis of intestines}
• _{Infectious diarrhoea}

INTRODUCTION:

It is defined as a pus filled mass in the liver that can develop from injury to the liver or an intrabdominal infection disseminated from the portal circulation. It is caused due to formation of germs like bacteria, parasites and fungus. Liver abscess can cause serious problem if left untreated. Infection can spread TO the liver through biliary tree, hepatic vein, portal vein or as a result of trauma.

CAUSES OF LIVER ABSCESS:

1. Abdominal infection such as appendicitis, perforated bowel and diverticulitis.
2. Infection in the blood
3. Injury to the liver.
4. Bacterial causes of liver abscess are streptococcus, Escherichia, Klebsiella species.
5. Infection in the bile duct.
6. Endoscopy of the bile draining tubes.

TYPES OF LIVER ABSCESS:

1. Pyogenic liver abscess: Pyogenic means pus.It is a pus filled pocket of fluid within the liver.
2. Amoebic liver abscess: It is the collection of pus in the liver in response to an intestinal parasite caused by Entamoeba histolytica.
3. Fungal abscess: It is due to the candida albicans and occur in person who have prolonged exposure of congenital and acquired immunodeficiency
4. Iatrogenic abscess: It is a complication of hepatic artery ligation for tumor.

SYMPTOMS OF LIVER ABSCESS:

1. Chest pain
2. Pain in right upper abdomen
3. Clay colored stools
4. Dark urine
5. Nausea
6. Vomiting
7. Jaundice
8. Fever
9. Night sweats
10. Decreased appetite
11. Weight loss
12. Pain radiating to right shoulder.

INVESTIGATION:

1. CT-scan
2. USG
3. Complete blood count
4. Liver biopsy
5. Liver function Tests

RISK FACTORS:

1. More intake of alcohol
2. Obesity
3. Type 2 Diabetes mellitus.`
4. Biliary tract disease
5. Age more than 50 years

DIFFERENTIAL DIAGNOSIS:

1. Viral hepatitis
2. Cholecystitis
3. Cholangitis
4. Necrotic liver masses

AYURVEDIC APPROACH OF LIVER ABSCESS:

In Ayurveda it is compared with Yakrit Vidradi. The dosha located around the organ or bone tissue it gets vitiated and affects the twak, rakta, mamsa and meda and will produce swelling and gradually develops into bigger size and pus is formed inside the cavity. Vidradhi are deep located and associated with pain.

GOOD HERBS IN YAKRIT VIDRADHI:

1. Kutki
2. Giloy
3. Yava
4. Bhumi amalaki
5. Shunthi
6. Turmeric
7. Garlic
8. Astragalus
9. Cardamom
10. Liquorice

PATHYA AHARA:

• Horse gram
• Garlic
• Drumstick
• Bitter gourd
• Honey
• Bilwa

APATHYA AHAR:

1. Old red rice
2. Banana
3. Ice water

CHANDIGARH AYURVED CENTRE MEDICATION FOR THE TREATMENT OF LIVER ABSCESS:

1. Kutki Capsule

These herbal capsules are prepared from the standardized extract of Picrorhiza kurroa. The herb used in this capsule show anti-inflammatory and antioxidant properties. These properties help in treating liver cirrhosis naturally.

Recommended Dosage: Take two capsules twice a day with normal water.

2. Detox Premium Powder

This is a herbo-mineral preparation that contains following ingredients: Moti pishti, Parwal pishti, Shukta pishti, Giloy satav, Kamdudha ras, Jahar Mohra pishti, Akik pishti, Gandhak rasayan, Shankh bhasam, Sutshekhar ras, Sudhyog tab, Shwet parpati, Yavakshaar. Premium detox powder keeps your liver cell healthy. It clears away the toxins from the body and stimulates the function of the liver and increases the flow of bile

Recommended Dosage: Take one sachet twice a day with normal water.

3. Liver Care Syrup

It is a herbo-mineral Syrup which is purely ayurvedic formulation. CAC Liver Care syrup helps in balancing Pitta dosha. This Syrup enhances regeneration of liver cells, promote functions of liver, and improve blood flow from the liver. It helps in the treatment of fatty liver, Liver cirrhosis, Hepatitis, hepatomegaly, and obstructive Jaundice. CAC Liver Care syrup contains Ingredients like Kalmegh (Andrographis paniculata), Kutaki(Picrorhiza kurroa), Bhumi amla( phyllanthus niruri), Giloy(Tinopora Cordifolia), Yavakshar( Hordeum vulgare), Imli Kshar( Tamarindus indica), Mukta Shukta pisti etc. These herbs show Antioxidant, anti-inflammatory, Hepato-protective, properties. This syrup improves digestion, enhances appetite.

It shows results in Fatty Liver, Liver Cirrhosis, Hepatitis A, Hepatitis B, Hepatitis C, Liver Cancer, Hepatomegaly, Inherited diseases- Hemochromatosis and Wilson’s disease, and Jaundice.

DOSAGE– Take 2 tablespoon twice daily

4. Liver Care Tablet

It is a herbo-mineral tablet of size 650 MG and is a purely ayurvedic formulation. CAC Liver Care tablets help in balancing Pitta dosha. These tablets stimulate the growth of new liver cells, promote functions of liver, and improve blood flow from the liver. It helps in the treatment of fatty liver, Liver cirrhosis, Hepatitis, hepatomegaly, and obstructive Jaundice. CAC Liver Care Tablets contains Ingredients like Kalmegh (Andrographis paniculata), Kutaki(Picrorhiza kurroa), Bhumi amla( phyllanthus niruri), Giloy(Tinopora Cordifolia), Yavakshar( Hordeum vulgare), Imli Kshar( Tamarindus indica), Mukta Shukta pisti etc. it shows results in Hepatomegaly, Inherited diseases- Hemochromatosis and Wilson’s disease, Jaundice and Obstructive jaundice

DOSAGE: Take one tablet twice a day with normal water.

5. Panchsakar Churna

It is a herbo mineral and purely ayurvedic formulation. It mainly works on your Vata and pitta dosha of your body. It can cure Chronic Constipation and help relieve symptoms of Acidity, indigestion, Belching and colic pain. It acts as a mild Laxative and reduces Bloating. It works very efficiently on a disease named IBS (Irritable bowel syndrome) which is very common nowadays that affects your day to day activities. CAC Panchsakar churna is 100% natural and pure. It is prepared from various herbs like Haritaki, Shunthi, Swaran Patri, Shatapushpa, and Saindhav Lavan that show antioxidant, anti-inflammatory and laxative properties.PANCHSAKAR CHURNA contains Haritaki (Terminalia Chebula), Shunthi (Zingiber Officinale), Saindhava Lavana (Rock Salt), Svarna Patri (Cassia Angustifolia), Shatapushpa (Foeniculum Vulgare)

DOSAGE: Take one tablespoon at night with normal water.

It is a herbo-mineral tablet of 650 MG and is purely Ayurvedic formulation. It helps in reducing excess Kapha or mucous from the body, supports respiratory system, manages weight, helps to take out impurities or ama from the body, supports healthy detoxification, reduces swelling. It has many properties such as anti-inflammatory, analgesic, expectorant, and antioxidant. It is made up of equal parts of three herbs such as Pippali (Piper longum), Shunthi (Zingiber officinale), & Marich (Piper nigrum) that maintains the metabolism of body. The regular use of this tablet maintains the balance of thyroxine hormone and prevents hyperthyroidism naturally. It act as an Appetizer and it improves digestion, supports normal gastric function, and normal circulation.

INGREDIENTS OF  CAC TRIKATU TABLET ARE:

1. Pippali (Piper longum)
2. Shunthi (Zingiber officinale)
3. Marich (Piper nigrum)

DESCRIPTION OF INGREDIENTS:

• Sunthi

It helps in balancing vata dosha and effective remedy for pain relief. It is also called as universal medicine because it has many medicinal properties like analgesic, antioxidant, anti-microbial, hepato protective, immune modulatory nephron protective, neuroprotective. Due to its properties the herb can be used to treat multiple health issues such as joint pain, cramps, sore throat, heartburn, muscle pain, vomiting and hypertension. It is rich in essential oil, pungent constituents such as gingerol and shogaol.

• Pippali

It is an effective herb in managing cough and cold. It acts as bronchodilator, Decongestant and expectorant effects due to its kapha balancing properties. Pippali contains many phytochemicals piperine and piper longumine, flavonoids and steroids. Other names of pippali are Magadhi, Chapala,kana,Ushna,Teeksna . It promotes digestive fire because it pacifies vata and kapha .

• Marich:

Piper nigrum contain many medicinal properties such as anti-inflammatory, anti-cancer, anti-oxidant, anti-microbial, antidiarrheal, anthelmintic, antispasmodic, anti-stress and It is widely used in digestive disorders. Piperine possesses inhibition of prostaglandins release that helps to relieve joint and muscular pain.

USES OF TRIKATU TABLET:

1. Promotes appetite
2. Enhances cardiac Functioning
3. Boost metabolism
4. Help in weight loss
5. Reduce pain and inflammation
6. Treats hyperthyroidism.
7. Supports respiratory function.
8. Flatulence
9. Helps in Detoxification.
10. Belching
11. Gastritis
12. Expectorant

ALLOPATHIC COUNTERPART OF TRIKATU TABLET ALONG WITH ITS SIDE EFFECTS :

Papain and Fungal Diastase

This tablet contains Papain and Fungal Diastase as main ingredients. Diastase is a potent, powerful hydrolyzing enzyme complex obtained from controlled fermentation of fungi. It is a digestive enzyme that helps in breakdown of carbohydrates and transforms into sugar. Papain is also known as papaya proteinase I and it is extracted from raw papaya. It is a cysteine protease enzyme present in papaya, has proteolytic activity and helps in breakdown of proteins into smaller fragments called peptides and amino acids. This tablet is used as digestant to easy digestion, prevents pancreatitis and promotes the digestion of carbohydrates, fats, and proteins and helps in absorb the essential nutrients in intestine.

SIDE EFFECTS:

1. Abdominal pain
2. Nausea
3. Vomiting
4. Diarrhea
5. Stomach upset
6. Pain while urinating

These tablets are Purely herbal and Ayurvedic formulation. These tablets are unique blend of ayurvedic herbs like bilwa, nagarmotha, peppermint, dadim, shankh bhasm, dhania and kutaz that helps to maintain natural Ph level in stomach thus helps to control acidity, flatulence, gas and constipation. These tablets also aids in digestion of all types of food.

In Ayurved all digestive diseases are caused due to Vitiated Pitta dosha which in turn leading to ama formation. The ama formed causes digestive disorders and also causing various health condition. These tablets also have Pitta dosha pacifying properties.

INGREDIENTS OF CAC DIGESTION SUPPORT TABLET :

• KUTAJ CHHAL (Holarrhena antidysenterica) : It has antioxidant, anti-diarrheal and anti-inflammatory properties thus helps to reduce inflammation and other associated symptoms of IBS and ulcerative colitis. It also regulates the secretion of digestive juices thus improving absorption of essential nutrients.
• BELGIRI (Aegle marmeos) : It has anti-bacterial properties thus helps to manage many digestive issues. It have high content of tannin which reduces inflammation in stomach ulcers thus providing relief from its associated symptoms. It also have laxative properties which helps to clean intestine and prevent constipation.
• DHANIYA (Coriandrum sativum ) : It has bio-active compound Anthocyanins which have anti-inflammatory thus helpful in healing stomach ulcers and indigestion. It is helpful in removing Ama (toxins) from body thus improve absorption of nutrients and promotes digestion.
• DADIM (Punica granatum ) :It has pre-biotic fibers that are helpful to maintain gut health thus providing relief from digestive issues like gas, indigestion, bloating etc. It is excellent source of dietary fiber and also have anti-inflammatory properties.
• NAGARMOTHA (Cyperus rotundus ) : It has excellent digestive, carminative and anti-flatulent properties thus help to reduce bloating, constipation, flatulence, abdominal distention etc. It also have antacid property thus prevent excessive production of acids in stomach therefore treats ulcer, gastritis and indigestion.
• SHANKH BHASAM : It has anti-diarrheal and anti-spasmodic properties that helps to manage diarrhea in severe cases. It also helps to neutralize acidity by regulating acid secretion in stomach. It also helps to get rid of Ama thus aids in digestion.
• PEPPERMINT (Mentha piperita ) : It is helpful in managing symptoms like bloating, indigestion and gas. It also prevent the spasm in smooth muscles in gut thus improving abdominal cramps. It also contain good amount of dietary fibers thus helps to manage cholesterol and blood sugar levels.

USES OF CAC DIGESTION SUPPORT TABLET :

• Helps in digestion
• Flatulence
• Acidity
• Gas
• Pacifies Pitta and Vata doshas
• IBS
• Ulcerative colitis
• Relieves constipation
• Helps in proper absorption and assimilation of food particles

COMPARED TO CAC DIGESTION SUPPORT  TABLETS ITS ALLOPATHIC COUNTERPART IS LANSOPRAZOLE

Lansoprazole is in class of drugs known as Proton pomp inhibitors. It is helps to reduce acid production in stomach thus used in treatment of peptic ulcers, GRED etc.  It is administrated by oral route and take a few hours to start working in body. Its affect last for a couple of days.

MECHANISM OF ACTION

It tends to selectively inhibits the H+/K+ATPase  enzyme membrane in gastric parietal cells. H+/K+ATPase  enzyme catalyze final step in acid secretion thus by  inhibit this enzymes membrane lansoprazole reduce the production of acid by gastric parietal cells in stomach.

Lansoprazole is available in market under brand name :

• B-Lanso
• Cytolog
• Lancid
• Lancibay
• Protogut
• Mesopil
• Laz-30
• Lanspro

SIDE-EFFECTS :

• Diarrhea
• Dizziness
• Dry mouth or throat
• Headache
• Vomiting
• Constipation
• Itchy skin rashes
• Blurred vision
• Sweating
• Fever
• Liver dysfunction
• Myalgia
• Depression
• Palpitations
• Gas
• Muscle pain
• Anxiety
• Chest pain
• Seizures

INTERACTION WITH OTHER DRUGS :

• Sucralfate
• Iron salts
• Voriconaazole
• Astemizole
• Ampisilin
• Clopidogrel
• Fluvoxamine
• Voriconazole